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KMID : 0358819910180040612
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1991 Volume.18 No. 4 p.612 ~ p.619
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AN EXPERIMENTAL STUDY OFGLUTARALDEHYDE-TREATED HOMOGENOUS CARTILAGE GRAFT IN RABBITS
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Abstract
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Reconstruction of the ear is a difficult problem in plastic surgery and there is still no ideal material to reconstruct ear cartilage. Recently glutaraldehyde treatment have been shown to decrease the antigenecity and break-down of graft material. Herein we performed an experimental comparative study of glutaraldehyde-treated homogenous graft, and glutaraldehyde untreated homogenous graft and autogenous graft of ear cartilage in rabbits. Degree of foreign body inflammatory reaction, capsular formation, and weight reduction of ear cartilage grafts were analyzed in each group at 1s. week, 4th week, and 6th week. Glutaraldehydetreated homogenous ear cartilage grafts showed less foreign body reaction and weight reduction than glutaraldehyde untreated homogenous ear cartilage grafts and were well preserved in shape. Glutaraldehyde-treated homogenous ear cartilage grafts were comparable to autogenous grafts.
We conclude that glutaraldehyde-treated homogenous cartilage is a highly promising graft material for the reconstruction of ear. We might expect that glutaraldehyde-treated cadeveric cartilage can be used in the reconstruction of ear.
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